This video was recorded at our 2026 AGM.
Yi Ng from Newcastle university gives an overview of HSP, common approaches to management, and talks about clinical research into HSP.

01:03 Agenda
01:40 Overview of relevant parts of the nervous system
02:27 How muscles are affected by HSP
03:47 Muscle weakness
04:14 HSP plus (complex HSP) affects about 10%
05:14 Clinical management of HSP
05:48 Medication options
07:05 Physiotherapy
08:33 Occupational therapy
09:29 Orthotics
10:27 Neurogenic bladder
14:02 Prevalence of HSP
16:01 Understanding the effects of the different genes
17:30 Spastic Paraplegia Rating Scale
18:25 Differences between 'pure' and 'complex' progression
20:04 Which symptoms are most/least talked about in clinic
21:28 HSP quality of life scale
23:03 Ways of measuring HSP impact
24:32 HSP patient journey
26:02 Gene therapy/Medication development