What if depression isn’t a chemical imbalance? What if it’s a metabolic condition, rooted in problems with energy metabolism that affect thoughts, feelings, and behavior? And what if that dysfunction could be reversed through lifestyle interventions that target the root causes?

*“For the first time since I can remember, I felt the weight of depression lift from my mind.”*

In this video, leading clinicians, researchers, and experts by experience share how ketogenic therapy is being used to support brain health and improve depressive symptoms, especially in cases where traditional treatments have fallen short.

From personal transformations to emerging clinical data, this video explores the growing role of metabolic interventions in mental health care. These stories are real. The science is evolving. And the hope is very much alive.

➡️ *Want to learn more about the metabolic approach to depression?*

Visit our *Keto for Depression Topic Page*
🌐 https://www.metabolicmind.org/resources/topics/depression

There you’ll find:
- Scientific evidence and expert insights
- Real-life stories of healing and recovery
- Resources for those exploring ketogenic therapy for depression
- Information on treatment-resistant depression and alternative options

📌 Learn more about THINK+SMART, a community inspired framework that helps individuals employ metabolic therapies to improve mental health:
https://www.metabolicmind.org/thinksmart/

🔎 Have questions about how to apply metabolic therapies effectively? Submit them at https://metabolicmind.org/questions to be featured in a future Metabolic Mailbag episode.

*Experts Featured:*
- Dr. Iain Campbell
- Dr. Lori Calabrese
- Joe (KIND Trial Participant)
- Lily Zhang
- Nicole Laurent
- Ally Houston
- Dr. Georgia Ede
- Robyn Dobbins
- Eric Rodgers
- Dr. Achina Stein
- Dr. Jeff Volek
- Jenny Mitich
- Sarah (KIND Trial Participant)
- Dr. Chris Palmer

*Resources Mentioned:*
*A pilot study examining a ketogenic diet as an adjunct therapy in college students with major depressive disorder*
- https://doi.org/10.1038/s41398-025-03544-8

*Our Coverage of the KIND Trial*
- https://www.metabolicmind.org/resources/library/blog/perspectives-in-metabolic-psychiatry/new-research-a-ketogenic-diet-improved-depression-in-college-students/

*Ketogenic Diets and Depression and Anxiety: A Systematic Review and Meta-Analysis*
- https://doi.org/10.1001/jamapsychiatry.2025.3261

*Our Coverage of the JAMA Psychiatry Meta-Analysis*
- https://youtu.be/J5C6i9xmu_I

*Free CME Clinician Trainings:*
Are you a clinician who would like to learn more about the science behind these therapies and how to implement them in practice? Earn CME with our growing library of courses from some of the top experts in the field including Dr. Chris Palmer, Dr. Georgia Ede, Dr. Matthew Bernstein and Dr. Bret Scher with more coming soon.

Our courses have been made *FREE* by grants from Baszucki Group, so we can spread these powerful therapies as widely as possible. Earn CME/CNE credits:
https://www.metabolicmind.org/for-clinicians/trainings-courses/?utm_medium=organic-social&utm_source=youtube&utm_campaign=cme-yt

Follow our channel for more information and education from Bret Scher, MD, FACC, including interviews with leading experts in Metabolic Psychiatry.

Learn more about metabolic psychiatry and find helpful resources at https://metabolicmind.org/

*About us:*
Metabolic Mind is a non-profit initiative of Baszucki Group working to transform the study and treatment of mental disorders by exploring the connection between metabolism and brain health. We leverage the science of metabolic psychiatry and personal stories to offer education, community, and hope to people struggling with mental health challenges and those who care for them.

Our channel is for informational purposes only. We are not providing individual or group medical or healthcare advice nor establishing a provider-patient relationship. Many of the interventions we discuss can have dramatic or potentially dangerous effects if done without proper supervision. Consult your healthcare provider before changing your lifestyle or medications.